产品货号:
Z33603
中文名称:
BUB3抗体
英文名称:
Anti-BUB3 Antibody (Clone#19B93)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BUB3 Antibody (Clone#19B93) |
指标别名 | BUB3;BUB3L;hBUB3 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF,IP,FCM |
基因名称 | BUB3 |
克隆号 | 19B93 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Bub3 |
实际分子量 | 40KD |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | BUB3(BUDDING UNINHIBITED BY BENZIMIDAZOLES 3) is a protein that in humans is encoded by the BUB3 gene.And it is mapped on 10q26.13.Bub3 is also a protein involved with the regulation of the Spindle Assembly Checkpoint(SAC);though BUB3 is non-essential in yeast,it is essential in higher eukaryotes.As one of the checkpoint proteins,Bub3 delays the irreversible onset of anaphase through direction of kinetochore localization during prometaphase to achieve biorentation.Bub3 directs the localization of Bub1 at the kinetochore in order to activate the SAC.Bub3 also acts as a regulator in that it affects binding of Mad3 to Mad2.Using deletion analysis,the authors identified a domain of BUB1 that is required both for binding BUB3 and for kinetochore localization of BUB1. |
Uniprot ID | O43684 |
基因名全称 | BUB3 mitotic checkpoint protein |
蛋白名全称 | Mitotic checkpoint protein BUB3 |
推荐稀释比 | Western blot (WB) 1:1000~5000 IHC 1:50~1:200 ICC/IF 1:100~500 IP 1:50 FCM 1:50 |
相关搜索:BUB3抗体,BUB3单抗,Anti-BUB3 Antibody (Clone#19B93)